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MYP_019135
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Basic Information
Ceratotoxin-C (Insects, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C142H255N37O35
Standard
Sequence
SLGGVISGAKKVAKVAIPIGKAVLPVVAKLVG
Physicochemical Analysis
3040.77 Da
10.60
4.46
4.24
0.1392
1.16
0.59
0.40
8.76
152.19
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1118.40
-7.81
38.0
40.0
102.0
214.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002399 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0008791 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0014501 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 25923
50 μM
MIC
PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0025005 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Ceratotoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anti-mammalian cells
PaperEur. J. Biochem. 1996; 241:330-337 | http://www.ncbi.nlm.nih.gov/pubmed/8917427 PMID8917427 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917427/
RECORD: Rec_0032703 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperMolecular characterization of ceratotoxin C, a novel antibacterial female-specific peptide of the ceratotoxin family from the medfly Ceratitis capitata.
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