Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1269H1991N325O371S10

DescriptionStandard

        MSTAAFHLANTLHPAGIQRGLSNMLLSVLLLLTLISCICGENPAIQVILSNKGLQYGKHAGTDWIQKNLQNFSLPAISGEVDIGLLGSIDYTLSDITIIKCDLPEPSVEFYPDATGLKTSISGLSFALSGGWVVDYKTLEDRGSFNMAVFNLNVVSVMELGKDPNDHLSVSSVRCDAEVGDVDIQFYGGVSSWVFQVFVKHFKGRIISEIKNRICPKVKEGIANLESHLQTMNSIVAVYNSLKKYWRYLYTSYLP
    

Molecular Weight28056.99 Da

Isoelectric Point (pI)6.06

Net Charge (pH 7.0)-3.01

Net Charge (pH 7.4) -3.66

Charge Density (pH 7.0) -0.0118

GRAVY Index0.16

Hydrophobic Moment 0.70

Boman Index0.17

Instability Index21.82

Aliphatic Index 105.45

Aromaticity 0.0941

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385772 VERIFIED: NO

Provenance & Taxonomy

OrganismChanna argus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria