Peptide Database

Peptide NameRN3(5-17P22-36)[T4I]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC173H266N56O38S

DescriptionStandard

        RPFIRAQWFAIQHISPRTIAMRAINNYRWR
    

Molecular Weight3770.38 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.85

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.1949

GRAVY Index-0.49

Hydrophobic Moment 0.47

Boman Index-0.15

Instability Index60.23

Aliphatic Index 78.33

Aromaticity 0.1667

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1554.35

LogP -11.38

H-bond Donors 57.0

H-bond Acceptors 46.0

Rotatable Bonds 118.0

Heavy Atoms 268.0

Ring Count 10.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385280 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHep-G2

Activity95.78±6.37 μM

MethodIC50

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