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MYP_019099
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Basic Information
RN3(5-17P22-36)[T4I]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C173H266N56O38S
Standard
Sequence
RPFIRAQWFAIQHISPRTIAMRAINNYRWR
Physicochemical Analysis
3770.38 Da
12.00
5.85
5.59
0.1949
-0.49
0.47
-0.15
60.23
78.33
0.1667
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1554.35
-11.38
57.0
46.0
118.0
268.0
10.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054092 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
0.55
ED50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0082055 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
95.78
IC50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0135132 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
150 μM
IC50
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0287666 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Sheep erythrocytes: >150 μM
50 %
Hemolysis
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0327783 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>150 μM
IC50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
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