Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC430H678N124O124S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGVQELEEAGSNDTPVAAHQEMSMESWMMPNHIRQKRQSHLSLCRWCCNCCRGNKGCGFCCRF
    

Molecular Weight10017.65 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.14

Hydrophobic Moment 0.66

Boman Index0.09

Instability Index63.86

Aliphatic Index 71.56

Aromaticity 0.0778

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3960.38

LogP -41.52

H-bond Donors 146.0

H-bond Acceptors 142.0

Rotatable Bonds 329.0

Heavy Atoms 692.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190188 VERIFIED: YES

Provenance & Taxonomy

OrganismMicropterus salmoides [Animal]

FamilyHepcidin

Tax ID27706

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0249414 VERIFIED: NO