Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC590H944N164O189S9

DescriptionStandard

        MKLLLLALPMLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCVPSNEDHRQVPTASPTPLSDSTPGSIDDILTVRFTTDYFEVSSKKDMVEESEAEWGTQTSLPDVHHSS
    

Molecular Weight13647.38 Da

Isoelectric Point (pI)5.76

Net Charge (pH 7.0)-3.19

Net Charge (pH 7.4) -3.73

Charge Density (pH 7.0) -0.0259

GRAVY Index-0.47

Hydrophobic Moment 0.64

Boman Index-0.07

Instability Index44.10

Aliphatic Index 73.66

Aromaticity 0.0488

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5645.64

LogP -62.81

H-bond Donors 199.0

H-bond Acceptors 199.0

Rotatable Bonds 448.0

Heavy Atoms 952.0

Ring Count 21.0

Amide Bonds 129.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373707 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyBeta-defensin; Defensin

Tax ID61853

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic