Peptide Database

Peptide NameDiapause hormone DH-I

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC116H179N37O38S

DescriptionStandard

        TDMKDESDRGAHSERGALWFGPRL
    

Molecular Weight2731.95 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.75

Charge Density (pH 7.0) -0.0628

GRAVY Index-1.18

Hydrophobic Moment 0.44

Boman Index-0.27

Instability Index11.53

Aliphatic Index 40.83

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1227.21

LogP -13.80

H-bond Donors 44.0

H-bond Acceptors 39.0

Rotatable Bonds 90.0

Heavy Atoms 192.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061766 VERIFIED: NO

Provenance & Taxonomy

OrganismBombyx mori [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0108530 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyPyrokinin/PBAN

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0113322 VERIFIED: NO

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyDiapause hormone

Tax ID7091

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0316673 VERIFIED: NO

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyPyrokinin

Tax ID7091

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone