Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC269H429N69O85S5

DescriptionStandard

        METEKYLQVVEDEEIEQLVGGVGPGWVETLTKDCPGYKPYACITIAGQTICKRCR
    

Molecular Weight6150.02 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-3.52

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0641

GRAVY Index-0.29

Hydrophobic Moment 0.45

Boman Index0.02

Instability Index60.96

Aliphatic Index 79.64

Aromaticity 0.0727

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2478.83

LogP -21.69

H-bond Donors 88.0

H-bond Acceptors 87.0

Rotatable Bonds 203.0

Heavy Atoms 428.0

Ring Count 8.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334763 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria