Peptide Database

Peptide NameAntiviral protein I

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length313 amino acids

Chemical FormulaC1577H2493N415O469S14

DescriptionStandard

        MKSMLVVTISIWLILAPTSTWAVNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYVLVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQDVETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIGKISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVALLNYVGGSCQTTYNQNAMFPQLIMSTYYNYMVNLGDLFEGF
    

Molecular Weight35219.07 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)4.66

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0149

GRAVY Index-0.19

Hydrophobic Moment 0.59

Boman Index0.05

Instability Index34.39

Aliphatic Index 90.29

Aromaticity 0.0958

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43110.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160363 VERIFIED: YES

Provenance & Taxonomy

OrganismPhytolacca americana [Plant]

FamilyRibosome-inactivating protein

Tax ID3527

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide56-281, 107-128

Bio-Activity Profile

Function

Antiviral Replication inhibitor Anti-HIV

TargetHuman immunodeficiency virus (HIV)-1

Activity0.017 μM

MethodIC50

RECORD: Rec_0307408 VERIFIED: YES