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MYP_018964
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
8 amino acids
C32H55N9O12
Standard
Sequence
AGAVVNDL
Physicochemical Analysis
757.83 Da
4.05
-1.20
-1.39
-0.1504
1.05
0.42
0.41
-1.86
146.25
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
347.41
-3.83
11.0
11.0
23.0
53.0
0.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035005 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0058461 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0139023 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
residue-level stereochemical modification [Mixed]
DesaminoY
None
DesaminoY : 3-(4-hydroxyphenyl)propionic acid
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0365590 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral
Herpes simplex virus type 1
283 μM
IC50
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 Sep 15;262(26):12413-6. | DOI:Not available | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0366341 VERIFIED: YES
Provenance & Taxonomy
Human alphaherpesvirus 1 [Virus]
Virus-derived peptide
10298;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Herpes simplex virus 1 (Replication); BHK-21/C
283 μM
Ribonucleotide reductase assay
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
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