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MYP_018950
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
36 amino acids
C184H288N50O51S2
Standard
Sequence
ELPKLPDDKVLIRSRSNCPKGKVWNGFDCKSPFAFS
Physicochemical Analysis
4080.69 Da
9.25
2.82
2.61
0.0782
-0.59
0.33
-0.13
58.73
62.22
0.1111
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1632.65
-15.34
57.0
56.0
132.0
287.0
9.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184549 VERIFIED: YES
Provenance & Taxonomy
Oryctes rhinoceros [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0225044 VERIFIED: YES
Provenance & Taxonomy
Oryctes rhinoceros [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
And Staphylococcus aureus
PaperPubMed PMID: 12859949 | PubMed PMID: 12676931 PMID12859949;12676931 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12859949/
RECORD: Rec_0226969 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0232117 VERIFIED: YES
Provenance & Taxonomy
Oryctes rhinoceros [Animal]
Scarabaecin
72550
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
PaperBiochem Biophys Res Commun. 2003 Jul 25;307(2):261-6 | http://www.ncbi.nlm.nih.gov/pubmed/12859949 PMID12859949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12859949/
RECORD: Rec_0248810 VERIFIED: YES
Provenance & Taxonomy
Oryctes rhinoceros [Animal]
Abaecin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
PMID12859949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12859949/
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