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MYP_018915
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glutamate carboxypeptidase II inhibition ▸ Glutamate carboxypeptidase II inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Glutamate Carboxypeptidase Inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Thymidylate Synthase Inhibitor
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Regulatory peptide ▸ Stimulation activity
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Sweet peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
2 amino acids
C10H16N2O7
Standard
Sequence
EE
Physicochemical Analysis
276.24 Da
4.24
-2.16
-2.33
-1.0776
-3.50
0.48
-0.74
168.00
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
167.02
-1.39
5.0
5.0
9.0
19.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245440 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Model sensory peptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
PaperUmami peptides: assessment of their alleged taste properties. Z. Lebensm. Unters. Forsch., 205, 125-130, 1997
RECORD: Rec_0249817 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
>100 μM
Hemolysis
PMID26257894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26257894/
RECORD: Rec_0274864 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Stimulatory
PaperRingseis R., Motthes B., Lehmann V., Becker K., Sch?ps R., Ulbrich-Hofmann R., Eder K.. Peptides and hydrolysates from casein and soy protein modulate the release of vasoactive substances from human aortic endothelial cells. Biochim. Biophys. Acta Gen. Subj., 1721, 89-97, 2005.
RECORD: Rec_0297937 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Naproxen
Bio-Activity Profile
Anti-inflammatory Targeting
PaperSynthesis and preliminary evaluation in vitro of novel naproxen-dendritic peptide conjugates Evidence URLhttps://doi.org/10.1080/10717540903050738
RECORD: Rec_0306002 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Glutamate Carboxypeptidase Inhibitor
Glutamate carboxypeptidase II
PaperGoldman P., Levy C. C.. Carboxypeptidase G: purification and properties. Proc. Natl. Acad. Sci. USA, 58, 1299-1306, 1967.
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