Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC481H785N129O137S7

DescriptionStandard

        MKLFLVLIILLFEVPKDAARHRRCFSNVSGYCRKKCKLGETYEIACVNGKLCCINEDEKRQYQQVTEPPEPSRKPDLKLDYAILPTVTLSTISL
    

Molecular Weight10791.62 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0377

GRAVY Index-0.19

Hydrophobic Moment 0.64

Boman Index-0.05

Instability Index43.89

Aliphatic Index 97.45

Aromaticity 0.0745

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4303.20

LogP -35.94

H-bond Donors 154.0

H-bond Acceptors 149.0

Rotatable Bonds 362.0

Heavy Atoms 754.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128029 VERIFIED: NO

Provenance & Taxonomy

OrganismDelphinapterus leucas [Animal]

FamilyDefensin

Tax ID9749

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence