Peptide Database

Peptide NameKalata-B1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length124 amino acids

Chemical FormulaC582H961N153O174S12

DescriptionStandard

        MAKFTVCLLLCLLLAAFVGAFGSELSDSHKTTLVNEIAEKMLQRKILDGVEATLVTDVAEKMFLRKMKAEAKTSETADQVFLKQLQLKGLPVCGETCVGGTCNTPGCTCSWPVCTRNGLPSLAA
    

Molecular Weight13270.56 Da

Isoelectric Point (pI)7.50

Net Charge (pH 7.0)0.53

Net Charge (pH 7.4) 0.11

Charge Density (pH 7.0) 0.0042

GRAVY Index0.29

Hydrophobic Moment 0.60

Boman Index0.13

Instability Index44.75

Aliphatic Index 95.97

Aromaticity 0.0484

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5211.20

LogP -51.08

H-bond Donors 187.0

H-bond Acceptors 188.0

Rotatable Bonds 447.0

Heavy Atoms 921.0

Ring Count 12.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087063 VERIFIED: YES

Provenance & Taxonomy

OrganismOldenlandia affinis [other]

FamilyCyclotide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Cytolytic Anti-uterotonic Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0249631 VERIFIED: YES