Peptide Database

Peptide Namebradykinin

Function Ontology

Antimicrobial

Cardiovascular

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Membrane / Ion-channel modulation ▸ Ion channel modulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC57H87N19O12

DescriptionStandard

        RRPPGFTPFR
    

Molecular Weight1230.42 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.2760

GRAVY Index-1.38

Hydrophobic Moment 0.04

Boman Index-0.44

Instability Index124.06

Aliphatic Index 0.00

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 504.78

LogP -4.43

H-bond Donors 18.0

H-bond Acceptors 15.0

Rotatable Bonds 33.0

Heavy Atoms 88.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059773 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

Familybradykinin

Tax ID8346

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Cardiovascular Myotropic Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory

Activity1.6 μM

MethodKi

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0203184 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

Family-bradykinin

Structure & Mods

Configribosomal mature linear peptide [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Bio-Activity Profile

Function

Smooth muscle contraction Vasorelaxant

RECORD: Rec_0219838 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

Familybradykinin

Tax ID8346

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Cardiovascular Myotropic Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0299332 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial