Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC554H888N150O166S3

DescriptionStandard

        PDLNGHEKYGLGNVKYNISRIRVTAVEFPSASISLLPGTGIKLVIANASLTIDMNWSLRTWMFKDTGRSTGYISKVFVTAIFSTPLDHTGHTLISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12402.08 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index-0.01

Hydrophobic Moment 0.53

Boman Index0.10

Instability Index8.61

Aliphatic Index 94.91

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5064.13

LogP -55.02

H-bond Donors 183.0

H-bond Acceptors 176.0

Rotatable Bonds 409.0

Heavy Atoms 873.0

Ring Count 18.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418381 VERIFIED: NO

Provenance & Taxonomy

OrganismCrypturellus undulatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria