Peptide Database

Peptide NameProthyroliberin type A

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length236 amino acids

Chemical FormulaC1171H1877N365O388S3

DescriptionStandard

        QGIPAEEETGDRQTIDDIILQRAESLLLRSILKNIGDEDGANEGLTSQPEWLVKRQHPGKRYQEELEKRQHPGKREEDEDEDYDEVQKRQHPGKREDEFDSFVELQRRQHPGKRLILEQITENPAFLSELSKRQHPGKRYVMYYSKRQHPGRREVDDESDAGDLRELEKRQHPGKRYLDNTSPDLGANSPCDVLDPGCSKANLLLQLLDNVNKSRAEKRQHPGKRSAPVEDLTEQE
    

Molecular Weight27372.84 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-9.48

Net Charge (pH 7.4) -10.21

Charge Density (pH 7.0) -0.0401

GRAVY Index-1.37

Hydrophobic Moment 0.73

Boman Index-0.36

Instability Index80.25

Aliphatic Index 66.53

Aromaticity 0.0424

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258090 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus nerka [Animal]

FamilyTRH

Tax ID8023

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGln56 Pyroglutamylation; Pro58 Amidation; Gln70 Pyroglutamylation; Pro72 Amidation; Gln90 Pyroglutamylation; Pro92 Amidation; Gln109 Pyroglutamylation; Pro111 Amidation; Gln134 Pyroglutamylation; Pro136 Amidation; Gln148 Pyroglutamylation; Pro150 Amidation; Gln171 Pyroglutamylation; Pro173 Amidation; Gln220 Pyroglutamylation; Pro222 Amidation

Bio-Activity Profile

Function

Hormone Neuropeptide