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MYP_018784
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Basic Information
Nigrocin-PN
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C88H160N24O23S2
Standard
Sequence
GLLGKILGAGKKVLCGVSGLC
Physicochemical Analysis
1986.49 Da
9.39
2.74
2.50
0.1303
1.13
0.51
0.39
-1.52
143.81
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
743.61
-6.27
28.0
28.0
70.0
137.0
0.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0212747 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID35606468 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35606468/
RECORD: Rec_0225626 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pelophylax nigromaculatus [Synthetic]
Nigrocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli NCTC 10,418
8 μM
MIC
PaperA novel antimicrobial peptide found in Pelophylax nigromaculatus
RECORD: Rec_0235253 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID35606468 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35606468/
RECORD: Rec_0335638 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pelophylax nigromaculatus [Synthetic]
Nigrocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus NCTC 10,788
4 μM
MIC
PaperA novel antimicrobial peptide found in Pelophylax nigromaculatus
RECORD: Rec_0336841 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pelophylax nigromaculatus [Synthetic]
Nigrocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Klebsiella pneumoniae ATCC 13,883, Klebsiella pneumoniae ATCC 43,816
16 μM
MIC
PaperA novel antimicrobial peptide found in Pelophylax nigromaculatus
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