Peptide Database

Peptide NameT-181

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC169H289N47O55

DescriptionStandard

        IEKLKEAIRDTNKAVQSVQSSIGNLIVAIKSVQDY
    

Molecular Weight3859.38 Da

Isoelectric Point (pI)8.38

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0218

GRAVY Index-0.14

Hydrophobic Moment 0.71

Boman Index-0.02

Instability Index44.43

Aliphatic Index 119.71

Aromaticity 0.0286

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1704.73

LogP -18.18

H-bond Donors 58.0

H-bond Acceptors 56.0

Rotatable Bonds 137.0

Heavy Atoms 271.0

Ring Count 1.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042388 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman parainfluenza virus 3 [Virus]

FamilyVirus-derived peptide

Tax ID11216;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetHuman parainfluenza virus type 3 (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0215909 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral