Peptide Database

Peptide NameDermaseptin-AC

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC115H201N31O30S2

DescriptionStandard

        GMFTNMLKGIGKLAGKAALGAVKTLA
    

Molecular Weight2562.15 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1445

GRAVY Index0.65

Hydrophobic Moment 0.67

Boman Index0.30

Instability Index-20.13

Aliphatic Index 105.38

Aromaticity 0.0385

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 978.45

LogP -8.44

H-bond Donors 34.0

H-bond Acceptors 36.0

Rotatable Bonds 90.0

Heavy Atoms 178.0

Ring Count 1.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415779 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis callidryas [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

Targetmethicillin-resistant Staphylococcus aureus ATCC 43300

Activity2 μg/mL

MethodMIC

FIRST PREV 1 2 3

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