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MYP_018758
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Basic Information
Dermaseptin-AC
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
26 amino acids
C115H201N31O30S2
Standard
Sequence
GMFTNMLKGIGKLAGKAALGAVKTLA
Physicochemical Analysis
2562.15 Da
10.48
3.76
3.55
0.1445
0.65
0.67
0.30
-20.13
105.38
0.0385
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
978.45
-8.44
34.0
36.0
90.0
178.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017059 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID34908502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34908502/
RECORD: Rec_0053749 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 43816
2 μg/mL
MIC
PMID34908502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34908502/
RECORD: Rec_0077247 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse RBC [HC50= 76.55 μM]
76.55 μM
HC50
PMID34908502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34908502/
RECORD: Rec_0157975 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCYC 1467
2 μg/mL
MIC
PMID34908502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34908502/
RECORD: Rec_0160877 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis NCTC 12697
2 μg/mL
MIC
PMID34908502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34908502/
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