Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length469 amino acids

Chemical FormulaC2320H3726N592O653S23

DescriptionStandard

        KMSPCCLLALLALIPLTLAANPGVKVKLTDKGIEYGKQIGMASLQQKLKTIKVPDLSGTEKVPHVGKVKYSLTGMTIVNLGLPKSALVLVPGTGVSLAITNAFINLHGNWRVRYFRFMQDRGSFDLAVNGLTITANIAIKSDETGRPMVSTVNCVANVGRASIKFHGGASWLYNLFKSYIDKALRSALQKQICPLVADAITDMNQHLKTFNVLAKVDQYAEIEYSMGTSPTISKSSMEFSLKGEFYNIVKHQEPPFSPTPFSLPPQGNNMLYIGVSSFTPNSAGFVYNNAGALSLYVTDDMVINILLRIKERLCVLFQIAKRFPGMMMKLLVKTVKEPTISLEPNNVTVQASGTVTAYAIQPNTTLSPLFVLNMEGSVSAQLNVTGVKLAGAITLNKIEMTLGTSYVGQFQVRIIFSDALFPCLFIFIVSALIEKGFPLPSIGKMNLVNTQLQVLKDYMLIGTDVQFTG
    

Molecular Weight51097.47 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)15.15

Net Charge (pH 7.4) 14.50

Charge Density (pH 7.0) 0.0323

GRAVY Index0.25

Hydrophobic Moment 0.70

Boman Index0.18

Instability Index29.15

Aliphatic Index 103.90

Aromaticity 0.0832

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32235.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091126 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria