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MYP_018675
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Basic Information
A3-APO
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
19 amino acids
C106H176N38O23
Standard
Sequence
RPDKPRPYLPRPRPPRPVR
Physicochemical Analysis
2350.77 Da
12.00
5.76
5.55
0.3031
-2.13
0.37
-0.75
62.29
35.79
0.0526
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
971.75
-7.99
33.0
29.0
64.0
167.0
9.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315021 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 20031377 PMID20031377 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20031377/
RECORD: Rec_0327021 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0364046 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
64 μM
MIC
PMID29051620 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29051620/
RECORD: Rec_0377319 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
1-Amino cyclohexyl carboxylic acid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli BW25113
4 μg/mL
MIC
PMID29309652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29309652/
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