Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC232H404N62O63S2

DescriptionStandard

        CCGGIKKEIEAIKKEQEAIKKKIEAIEKLLQLTVWGIKQLQARIL
    

Molecular Weight5134.20 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)3.75

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.0833

GRAVY Index-0.13

Hydrophobic Moment 0.64

Boman Index-0.03

Instability Index61.28

Aliphatic Index 128.00

Aromaticity 0.0222

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2071.98

LogP -12.40

H-bond Donors 72.0

H-bond Acceptors 69.0

Rotatable Bonds 191.0

Heavy Atoms 359.0

Ring Count 2.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323750 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHIV gp41 N-peptide fusion inhibitor

Tax ID32630.0

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antiviral Anti-HIV Fusion inhibitor

TargetHIV-1 89.6

Activity0.008 μM

MethodIC50

RECORD: Rec_0324329 VERIFIED: YES