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MYP_018638
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
45 amino acids
C232H404N62O63S2
Standard
Sequence
CCGGIKKEIEAIKKEQEAIKKKIEAIEKLLQLTVWGIKQLQARIL
Physicochemical Analysis
5134.20 Da
9.35
3.75
3.49
0.0833
-0.13
0.64
-0.03
61.28
128.00
0.0222
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2071.98
-12.40
72.0
69.0
191.0
359.0
2.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073499 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
PaperPatent US 7811577 B2 Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
RECORD: Rec_0089887 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 N-peptide fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Fusion inhibitor
SHIV-89.6P
0.0069 μM
IC50
PaperCovalently stabilized chimeric coiled-coil HIV gp41 N-peptides with improved antiviral activity Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
RECORD: Rec_0173251 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 N-peptide fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Fusion inhibitor
HIV-1 HXB2
0.00004 μM
IC50
PaperCovalently stabilized chimeric coiled-coil HIV gp41 N-peptides with improved antiviral activity Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
RECORD: Rec_0189199 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 N-peptide fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Fusion inhibitor
HIV-1 BaL
0.00034 μM
IC50
PaperCovalently stabilized chimeric coiled-coil HIV gp41 N-peptides with improved antiviral activity Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
RECORD: Rec_0302412 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 N-peptide fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Fusion inhibitor
HIV-1 NL4-3
0.0001 μM
IC50
PaperCovalently stabilized chimeric coiled-coil HIV gp41 N-peptides with improved antiviral activity Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
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