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MYP_018555
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Basic Information
Islet amyloid polypeptide
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C167H273N51O54S2
Standard
Sequence
KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
Physicochemical Analysis
3923.39 Da
9.50
2.74
2.50
0.0740
-0.25
0.67
-0.01
25.38
73.78
0.0541
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1718.07
-25.05
60.0
59.0
122.0
274.0
5.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0238426 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Calcitonin
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-7
Bio-Activity Profile
Hormone Calcium-regulatory peptide
PMID2679555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2679555/
RECORD: Rec_0280454 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
calcitonin family
10116; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
2-7
Bio-Activity Profile
Hormone calcitonin family
PaperPDB 2KJ7 structural record; NMR; chain A; residues 1-37
RECORD: Rec_0304139 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 45.9%, E 0.0%, T 29.7%, C 24.3% [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-7
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0305696 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]; Rattus norvegicus [Animal]
10090; 10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0407093 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]; Rattus norvegicus [Animal]
10090; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
2-7
Bio-Activity Profile
-
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