Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length525 amino acids

Chemical FormulaC2608H4120N686O737S19

DescriptionStandard

        MLKTWYSFLLCCLSLRLEANPGLKVRITQKGLDYGSRIGMELLKQALLRETFPSWSGQESFSVVKVNYVISRLRINAVDFPETSASFIPGTGISLSVAHASATISADWRMNTWLLKDQGGITVSISGLFIAVIFKVSRDTTGRLYILLHNCQLSINSLKVKLNGGSSWIYSFLSGYLEKPIHTKLDKNGTVYPVGSHTEPPFVPAPFDFPNQGDSMLYLGVSSYFIKSASLAYYRAGVFNITISKELATTFNLNTALFKDFVPEIALSYVTACPVLLKLMATSPPAVSLNADRCILQITGCVEVFAVLPNSTTQYIFRGNLTASTRGNLTITKQKLIISLLLKRFQFSLLHSILGFSEQISLVENFLSYALRSAVIPVINGKDCGQFLSTIGRKARLKPYKGVPTFKDRVMGGSLTVWLHLDRSALCWTSVQVPQSPGSGAGTEQVLAPFQTAGLGFLFTGCSVAAELRHKLEFCPDTESSHDRRMAQTGEVQKHAYSLGLRGDISNFITSLCLCASPAAAGRTK
    

Molecular Weight57486.00 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)18.19

Net Charge (pH 7.4) 17.24

Charge Density (pH 7.0) 0.0346

GRAVY Index0.17

Hydrophobic Moment 0.72

Boman Index0.14

Instability Index30.14

Aliphatic Index 98.63

Aromaticity 0.0990

Extinction Coeff. Reduced 62340.00

Extinction Coeff. Oxidized 63090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190405 VERIFIED: NO

Provenance & Taxonomy

OrganismAccipiter nisus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria