Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC64H111N25O21

DescriptionStandard

        GRTTLSTRGPPRGGPG
    

Molecular Weight1566.72 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.1725

GRAVY Index-1.21

Hydrophobic Moment 0.45

Boman Index-0.26

Instability Index13.80

Aliphatic Index 24.38

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 740.07

LogP -12.68

H-bond Donors 27.0

H-bond Acceptors 24.0

Rotatable Bonds 46.0

Heavy Atoms 110.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179209 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Protease inhibitor Replication inhibitor

TargetCoxsackievirus (Replication); HeLa

MethodWestern blotting

PaperTargeting enteroviral 2A protease by a 16-mer synthetic peptide: inhibition of 2Apro-induced apoptosis in a stable Tet-on HeLa cell line. | Maghsoudi N, Tafreshi NKh, Khodagholi F, Zakeri Z, Esfandiarei M, Hadi-Alijanvand H, Sabbaghian M, Maghsoudi AH, Sajadi M, Zohri M, Moosavi M, Zeinoddini M. | Virology. 2010 | PMID:20096913 PMID20096913 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20096913/

RECORD: Rec_0281392 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 12.5%, T 43.8%, C 43.8% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial