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MYP_018465
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Basic Information
Beta defensin 1(BD-1; mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
36 amino acids
C169H292N64O45S6
Standard
Sequence
QRYFCRVRGGRCAALTCLPRETQIGRCSVKGRKCCR
Physicochemical Analysis
4132.92 Da
10.35
8.70
8.40
0.2417
-0.53
0.54
-0.38
12.05
54.17
0.0556
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1824.67
-22.83
75.0
60.0
140.0
284.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027263 VERIFIED: YES
Provenance & Taxonomy
Chinchilla lanigera [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
12.5-20 μg/mL
MIC
PMID14996845 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14996845/
RECORD: Rec_0046387 VERIFIED: YES
Provenance & Taxonomy
Chinchilla lanigera [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Streptococcus pneumoniae
5 μg/mL
MIC
PMID14996845 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14996845/
RECORD: Rec_0057500 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0130898 VERIFIED: YES
Provenance & Taxonomy
Chinchilla lanigera [Animal]
Defensin
34839
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
12.5-20 μg/mL
MIC
PaperIdentification and characterization of a mucosal antimicrobial peptide expressed by the chinchilla (Chinchilla lanigera) airway PMID14996845 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14996845/
RECORD: Rec_0188811 VERIFIED: YES
Provenance & Taxonomy
Chinchilla lanigera [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Moraxella catarrhalis
5 μg/mL
MIC
PMID14996845 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14996845/
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