Peptide Database

Peptide NameS13

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC159H265N57O37S2

DescriptionStandard

        EMFTILEEYFMYRGLLGLRRRRRRRRR
    

Molecular Weight3631.29 Da

Isoelectric Point (pI)11.83

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.66

Charge Density (pH 7.0) 0.2533

GRAVY Index-1.13

Hydrophobic Moment 0.57

Boman Index-0.62

Instability Index205.05

Aliphatic Index 72.22

Aromaticity 0.1481

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1611.51

LogP -12.01

H-bond Donors 64.0

H-bond Acceptors 46.0

Rotatable Bonds 127.0

Heavy Atoms 255.0

Ring Count 4.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213121 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays