Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC429H681N117O108S11

DescriptionStandard

        MKLLLLFLVIFLAVEPVMSGRHSLLRCMGSMGVCRTACRKIEHTYFYCRNYQSCCLQSFMRINVAGKDEPGVLSYAKHWPKIP
    

Molecular Weight9558.43 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.70

Net Charge (pH 7.4) 6.23

Charge Density (pH 7.0) 0.0808

GRAVY Index0.23

Hydrophobic Moment 0.69

Boman Index0.10

Instability Index62.81

Aliphatic Index 91.57

Aromaticity 0.1084

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3582.01

LogP -25.98

H-bond Donors 133.0

H-bond Acceptors 129.0

Rotatable Bonds 313.0

Heavy Atoms 665.0

Ring Count 17.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310476 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence