Peptide Database

Peptide NamePleurain-M1 antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC343H582N88O108S4

DescriptionStandard

        MFTLKKTLLLIFVLGTISLSLCEQERGADEDEGEAVEEIKRGLLDSVKEGLKKVAGQLLDTLKCKISGCTPA
    

Molecular Weight7795.08 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0349

GRAVY Index0.08

Hydrophobic Moment 0.67

Boman Index0.06

Instability Index22.99

Aliphatic Index 113.75

Aromaticity 0.0278

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3168.44

LogP -27.96

H-bond Donors 112.0

H-bond Acceptors 110.0

Rotatable Bonds 277.0

Heavy Atoms 543.0

Ring Count 3.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387601 VERIFIED: YES

Provenance & Taxonomy

OrganismRana pleuraden [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0401791 VERIFIED: YES

Provenance & Taxonomy

OrganismNidirana pleuraden [Animal]

Tax ID369511

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal