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MYP_018223
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Basic Information
Pseudin-1 (Pseudin 1; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
24 amino acids
C123H204N36O33
Standard
Sequence
GLNTLKKVFQGLHEAIKLINNHVQ
Physicochemical Analysis
2715.16 Da
9.70
1.93
1.62
0.0806
-0.14
0.69
0.07
-8.10
125.83
0.0417
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1141.02
-9.62
37.0
37.0
95.0
192.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008910 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
PaperPubMed PMID: 11689009 PMID11689009 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11689009/
RECORD: Rec_0058521 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Escherichia coli
4.5 μM
MIC
PaperPseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.
RECORD: Rec_0120125 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Pseudin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID11689009 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11689009/
RECORD: Rec_0156064 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Human immunodeficiency virus 1 (HIV-1)
35.7 μM
EC50
PaperPseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.
RECORD: Rec_0159832 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Frog skin active peptide (FSAP); Pseudin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Non-hemolytic
Escherichia coli
PMID11689009 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11689009/
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