Peptide Database

Peptide Namehepcidin TH2-3

Function Ontology

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Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC88H137N31O25S5

DescriptionStandard

        QSHMSLCRYCWNCCRNKG
    

Molecular Weight2189.55 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)2.81

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.1559

GRAVY Index-0.84

Hydrophobic Moment 0.64

Boman Index-0.30

Instability Index87.78

Aliphatic Index 21.67

Aromaticity 0.1111

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 942.27

LogP -11.92

H-bond Donors 38.0

H-bond Acceptors 34.0

Rotatable Bonds 71.0

Heavy Atoms 149.0

Ring Count 4.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165122 VERIFIED: YES

Provenance & Taxonomy

OrganismClupea harengus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)