Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC921H1485N259O270S12

DescriptionStandard

        MKNPLSKQMTALLTAFAMGGTGTVVVTQTDILNQFLNEKEGNRLTAYLDSANPPIWTICRGVTRIDGKPVTKGMRLTEKQCDLLNDKEAQKSLKWVRDNIPVKLNPVQQVGIASFCPYNIGPTKCKGSTFFKLLQKGDWKNACKQIPRWVFDGGKDCRIKSNNCSGQPIRREQEEYLCLYTLGESK
    

Molecular Weight20891.00 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)10.43

Net Charge (pH 7.4) 10.04

Charge Density (pH 7.0) 0.0561

GRAVY Index-0.49

Hydrophobic Moment 0.79

Boman Index-0.07

Instability Index31.70

Aliphatic Index 76.51

Aromaticity 0.0753

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8624.71

LogP -105.35

H-bond Donors 301.0

H-bond Acceptors 293.0

Rotatable Bonds 705.0

Heavy Atoms 1462.0

Ring Count 28.0

Amide Bonds 208.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229859 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage vB_KpnM_15-38_KLPPOU148 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic