Peptide Database

Peptide NameAlpha-defensin 3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC450H717N135O144S7

DescriptionStandard

        MRTIAILAAILLFSLQAQAESLQERADEVATQEQPGEDDQDFAVSFEENGLSTLRASGSQARHTCYCRNKRCFTPEFHAGKCKVEGRTYKLCCR
    

Molecular Weight10546.78 Da

Isoelectric Point (pI)6.09

Net Charge (pH 7.0)-1.36

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0145

GRAVY Index-0.47

Hydrophobic Moment 0.47

Boman Index-0.13

Instability Index44.81

Aliphatic Index 66.60

Aromaticity 0.0745

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4564.61

LogP -53.13

H-bond Donors 165.0

H-bond Acceptors 152.0

Rotatable Bonds 357.0

Heavy Atoms 736.0

Ring Count 11.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070623 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function