MYP_018032
Malanin chain B (Plant defensin)
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
DETXTDEEFN
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0018140
VERIFIED: YES
Provenance & Taxonomy
Malania oleifera [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Anticancer
Cytotoxic
K562
0.0158±0.00009 μM
IC50
RECORD: Rec_0019084
VERIFIED: YES
Provenance & Taxonomy
Malania oleifera [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Anticancer
Cytotoxic
Non-cancer cell lines: Vero (IC50=2.79±0.05 nM) and Madin-Darby canine kidney cells
0.00392±0.00001 μM
IC50
RECORD: Rec_0187036
VERIFIED: YES
Provenance & Taxonomy
Malania oleifera [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Anticancer
Cytotoxic
Cancer cell lines: HeLa
0.00015±0.00008 μM
IC50
RECORD: Rec_0235764
VERIFIED: YES
Provenance & Taxonomy
Malania oleifera [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Anticancer
Cytotoxic
MCF-7
0.0112±0.00002 μM
IC50
RECORD: Rec_0248633
VERIFIED: YES
Provenance & Taxonomy
Malania oleifera [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Anticancer
Cytotoxic
PC-12
0.00771±0.00024 μM
IC50