Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC420H701N121O115S9

DescriptionStandard

        MKLLSLTLAALLLLSQLTPGSTQKCWNLHGRCRQKCSRKERIYVYCTNNKLCCVKPKYQPREKLWSSSSKPEAMKTQMKLPSV
    

Molecular Weight9574.39 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)12.52

Net Charge (pH 7.4) 12.14

Charge Density (pH 7.0) 0.1509

GRAVY Index-0.48

Hydrophobic Moment 0.48

Boman Index-0.15

Instability Index32.97

Aliphatic Index 79.88

Aromaticity 0.0602

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3862.08

LogP -38.17

H-bond Donors 142.0

H-bond Acceptors 138.0

Rotatable Bonds 326.0

Heavy Atoms 665.0

Ring Count 13.0

Amide Bonds 90.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0150164 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera tigris altaica [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence