Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC758H1208N230O238S9

DescriptionStandard

        MGRLMLTLVLCALLAQVTEGSWGIKRCWKNDVGHCRRRCLDDERYIRLCRNKLSCCISLTLSYDITRRPPPPVINIEGFTDSFDEDQFSASPVSRLSDEVTFFGTPETRAPTSQTVTTEHTTPGVLANSAGSGSSLQGANATSAIPRGRLHWRQDNHGDG
    

Molecular Weight17639.68 Da

Isoelectric Point (pI)7.61

Net Charge (pH 7.0)0.81

Net Charge (pH 7.4) 0.26

Charge Density (pH 7.0) 0.0050

GRAVY Index-0.40

Hydrophobic Moment 0.63

Boman Index-0.07

Instability Index53.54

Aliphatic Index 73.75

Aromaticity 0.0625

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7535.21

LogP -91.84

H-bond Donors 274.0

H-bond Acceptors 252.0

Rotatable Bonds 573.0

Heavy Atoms 1235.0

Ring Count 26.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108367 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence