Peptide Database

Peptide NameTNGPQLIH

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC38H62N12O12

DescriptionStandard

        TNGPQLIH
    

Molecular Weight878.97 Da

Isoelectric Point (pI)6.40

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.76

Charge Density (pH 7.0) -0.0643

GRAVY Index-0.57

Hydrophobic Moment 0.43

Boman Index0.12

Instability Index10.68

Aliphatic Index 97.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 393.32

LogP -4.49

H-bond Donors 12.0

H-bond Acceptors 13.0

Rotatable Bonds 26.0

Heavy Atoms 62.0

Ring Count 2.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076154 VERIFIED: YES

Provenance & Taxonomy

OrganismCannabis sativa [Plant]

Tax ID3483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory Antidiabetic

TargetDPP-IV

Activity1.70 mg/mL

MethodIC50