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MYP_017892
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Basic Information
Vasoactive intestinal peptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory ▸ attenuation of acute inflammation
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Metabolic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
28 amino acids
C147H237N43O43S
Standard
Sequence
HSDAVFTDNYTRLRKQMAVKKYLNSILN
Physicochemical Analysis
3326.78 Da
9.82
2.84
2.58
0.1016
-0.64
0.60
-0.18
32.19
83.57
0.1071
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1447.90
-14.62
51.0
48.0
113.0
234.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0263991 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0272078 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Lactobacillus acidophilus
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
RECORD: Rec_0284909 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Escherichia coli 25922
8 μM
MIC
Paper抗菌肽VIP在毕赤酵母中的高效表达及鉴定; Expression and identification of an antimicrobial peptide VlP in Pichiapastoris. [J].生物工程学报,2018,34(06):1002-1011. DOI:10.13345/j.cjb.170506. PMID29943546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29943546/
RECORD: Rec_0286321 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2342988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2342988/
RECORD: Rec_0299763 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
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