Peptide Database

Peptide NameAgouti-related protein

Function Ontology

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Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC532H863N161O157S11

DescriptionStandard

        VQMGVAPLKGIRRPDQALFPEFPGLSLNGLKKTTADRAEEVLLQKAEALAEVLDPQNRESRSPRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTATNLCSRT
    

Molecular Weight12379.24 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.31

Charge Density (pH 7.0) 0.0427

GRAVY Index-0.30

Hydrophobic Moment 0.88

Boman Index-0.11

Instability Index48.26

Aliphatic Index 73.87

Aromaticity 0.0631

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5137.87

LogP -56.69

H-bond Donors 187.0

H-bond Acceptors 174.0

Rotatable Bonds 406.0

Heavy Atoms 861.0

Ring Count 16.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344439 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0432275 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAgouti-related protein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Melanocortin receptor antagonist

Targetmelanocortin-3 receptor; melanocortin-4 receptor

Methodreceptor antagonism assay