Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2387H3804N630O650S12

DescriptionStandard

        MTTRRLALAASVLAICTVLTRATNPGFVARITVKGLDYARQEGIAALQKELAKLKLPDFSGTFKVKLLGKVHYTFYSLNLRSFQLPSSQIAPIPNVGLKVSIANAFAQLRGKWRVKKRFIRDSGSFDLKVEGLSISIGLKLGSDASGRPTVTTSECGTHISNVRVHISGRFGWLYNLFHKKIESSFRRTMEGKVCGAVTSSVTTKLQPYLQTVPVTAKIDKVAGIDYSLVAPPAATAQSLDLNLKGEFFSLAHRSAVPFPPPALAFPVDHDRMVYCGASSYFFNTAGFVYHTAGALLFEITDAMIPKEFKFHLNTSTFSAFIPQLEKMYPDKLMKLRIKTSSAPFLTITPGNLSLTPVVDIQAYVILPNSSLVPVFLLSVTSSVSAKIMVTSARIGGTLELGRLQLSLKHSDVGPFSVQLLQALMNFYGSSILIPRINARLKEGFPLPLPARIQLSNLVIQPHQNFLLFGADVRYV
    

Molecular Weight52112.35 Da

Isoelectric Point (pI)10.01

Net Charge (pH 7.0)26.34

Net Charge (pH 7.4) 25.47

Charge Density (pH 7.0) 0.0553

GRAVY Index0.20

Hydrophobic Moment 0.74

Boman Index0.14

Instability Index37.16

Aliphatic Index 102.23

Aromaticity 0.0945

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0134232 VERIFIED: NO

Provenance & Taxonomy

OrganismTerrapene carolina triunguis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria