Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC555H879N145O171S3

DescriptionStandard

        PDLNGYEKYGLGNVKYNISEIHVTAVEFPNASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDTGRSTVYISKVFVTAIFSTPLDNTGHTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12414.98 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)1.13

Net Charge (pH 7.4) 0.93

Charge Density (pH 7.0) 0.0099

GRAVY Index-0.03

Hydrophobic Moment 0.49

Boman Index0.13

Instability Index9.59

Aliphatic Index 93.16

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5078.22

LogP -55.47

H-bond Donors 180.0

H-bond Acceptors 177.0

Rotatable Bonds 408.0

Heavy Atoms 874.0

Ring Count 18.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220961 VERIFIED: NO

Provenance & Taxonomy

OrganismGlareola pratincola (Collared pratincole) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria