Peptide Database

Peptide NameAntimicrobial peptide Esculentin-2HB2

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC170H273N45O48S2

DescriptionStandard

        GFFSLFSTAAKFLGKTLLKQAGKAGAEAVACKATNQC
    

Molecular Weight3779.39 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1010

GRAVY Index0.30

Hydrophobic Moment 0.58

Boman Index0.17

Instability Index10.68

Aliphatic Index 71.62

Aromaticity 0.1081

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1508.74

LogP -16.75

H-bond Donors 54.0

H-bond Acceptors 54.0

Rotatable Bonds 128.0

Heavy Atoms 265.0

Ring Count 4.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114994 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax hubeiensis [Animal]

FamilyEsculentin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant