Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC356H570N100O88S8

DescriptionStandard

        MPGAMKIFFFIFAALILLAQIFQARTAIHRALISKRMEGHCEAECLTFEVKTGGCRAELAPFCCKNRKKH
    

Molecular Weight7915.47 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 5.26

Charge Density (pH 7.0) 0.0817

GRAVY Index0.27

Hydrophobic Moment 0.44

Boman Index0.09

Instability Index39.31

Aliphatic Index 85.29

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3001.99

LogP -21.74

H-bond Donors 110.0

H-bond Acceptors 105.0

Rotatable Bonds 267.0

Heavy Atoms 552.0

Ring Count 12.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084879 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0312768 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyBeta-defensin; Defensin

Tax ID9598

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic