Peptide Database

Peptide NameAlpha-like toxin BmK-M1

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC313H475N91O91S8

DescriptionStandard

        VRDAYIAKPHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIRVPGKCH
    

Molecular Weight7225.19 Da

Isoelectric Point (pI)8.17

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.38

Charge Density (pH 7.0) 0.0286

GRAVY Index-0.53

Hydrophobic Moment 0.55

Boman Index-0.06

Instability Index29.29

Aliphatic Index 59.38

Aromaticity 0.1094

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2933.24

LogP -29.75

H-bond Donors 107.0

H-bond Acceptors 103.0

Rotatable Bonds 228.0

Heavy Atoms 503.0

Ring Count 15.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148126 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense