Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Reproductive biology ▸ Contraceptive activity ▸ Spermicidal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC119H206N32O33

DescriptionStandard

        GIGGVLLSAGKAALKGLAKVLAEKYAN
    

Molecular Weight2613.10 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1021

GRAVY Index0.59

Hydrophobic Moment 0.59

Boman Index0.28

Instability Index7.25

Aliphatic Index 130.37

Aromaticity 0.0370

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1044.85

LogP -8.94

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 91.0

Heavy Atoms 184.0

Ring Count 1.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420454 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyMaximin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral Anticancer

TargetKlebsiella pneumoniae

Activity15 μg/mL

MethodMIC

PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703. | Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/

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