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MYP_017726
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Basic Information
Caerin-1.19 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C127H212N32O29
Standard
Sequence
GLFKVLGSVAKHLLPHVAPIIAEKL
Physicochemical Analysis
2651.24 Da
9.70
1.93
1.62
0.0774
0.90
0.59
0.37
12.20
156.00
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.09
-2.92
31.0
33.0
86.0
188.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0294208 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
50 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0294600 VERIFIED: YES
Provenance & Taxonomy
Australian dainty green [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Bacillus cereus
50 μg/mL
MIC
PaperNew caerin antibiotic peptides from the skin secretion of the Dainty Green Tree Frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry
RECORD: Rec_0314405 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Strain ATCC 29213
12 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0317139 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Pasteurella multocida
50 μg/mL
MIC
PMID26026377;16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
RECORD: Rec_0334249 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Staphylococcus epidermidis
12 μg/mL
MIC
PMID26026377;16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
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