‹ ›
MYP_017726
← PREVIOUS NEXT → BACK
Basic Information
Caerin-1.19 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C127H212N32O29
Standard
Sequence
GLFKVLGSVAKHLLPHVAPIIAEKL
Physicochemical Analysis
2651.24 Da
9.70
1.93
1.62
0.0774
0.90
0.59
0.37
12.20
156.00
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.09
-2.92
31.0
33.0
86.0
188.0
5.0
24.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0121192 VERIFIED: YES
Provenance & Taxonomy
Ranoidea gracilenta [Animal]
Frog skin active peptide (FSAP); Caerin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Gram-negative and Gram-positive bacteria
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0151242 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Leuconostoc lactis
3 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0153378 VERIFIED: YES
Provenance & Taxonomy
Chlorohyla gracilenta [Animal]
Caerin
3681121
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Release inhibition
HIV | T cells
2.5 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of HIV infection by caerin 1 antimicrobial peptides. | VanCompernolle S, Smith PB, Bowie JH, Tyler MJ, Unutmaz D, Rollins-Smith LA. | Peptides. 2015 Sep;71:296-303. | DOI:10.1016/j.peptides.2015.05.004 | PMID:26026377 PMID26026377 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
RECORD: Rec_0164982 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
PMID26026377;16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
RECORD: Rec_0208500 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Staphylococcus aureus Strain ATCC 25923
12 μg/mL
MIC
PMID26026377;16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
FIRST PREV 1 2 3 4 5 ... 7 NEXT LAST
Showing 5 records on this page · Page 3 of 7